Diseases

Purpura: the causes

What are the possible causes of purpura? Two major mechanisms may be responsible for the disease:

1. An abnormality of blood clotting.

It is a platelet deficiency (thrombocytopenia). The platelet count is then lowered below 50 Giga / L. On the other hand, in case of platelet malformation (thrombopathy) the platelet count may be normal and it is then the bleeding time that is lengthened.

The diseases responsible for this type of purpura are:

  • certain autoimmune diseases (idiopathic thrombocytopenic purpura, lupus ...)
  • abnormalities of platelets or vessels of hereditary genetic origin
  • hematological diseases (leukemias, lymphomas)
  • certain cancers
  • Excessive consumption of platelets due to infection (disseminated intravascular coagulation)
  • a drug by allergic mechanism

2. An abnormality of the vessel wall of the skin.

The level of platelets in the blood is then normal. When the vessel wall is inflamed, it is called vasculitis.

Several conditions may be involved:

  • an infection (virus, meningitis or bacteria on a heart valve (endocarditis))
  • an inflammatory rheumatoid disease (rheumatoid purpura)
  • a drug by inflammatory mechanism
  • fragility of the skin due to aging (senile purpura) or long-term oral cortisone treatment (Bateman purpura). A purpura then appears at the slightest shock often on the front arms and legs.
  • a secondary reaction to certain cancers

Other causes that may be at the origin of purpura

Other causes such as rubbing a sock elastic or vitamin C deficiency can cause purpura lesions.

Chest or abdominal hyperpressions such as vomiting may also be responsible.

Venous insufficiency can also cause typical purpuric lesions called ocher dermatitis or eczematide like-purpura.

To see: pimples or patches on the skin: what disease can it be?

You want to react, to give your testimony or to ask a question? Appointment in our FORUMS Skin diseases or A doctor answers you !

To read :

> Rash: what disease can it be?
> Thrombocytopenia (platelet decline) following chemotherapy
> Anticoagulants: how does it work?

Popular Posts

Category Diseases, Next Article

Hip fever: Treatments - Diseases
Diseases

Hip fever: Treatments

The hip cold heals spontaneously. There is therefore no cure for this condition. The child may be given symptomatic treatment for pain, and may prescribe rest ... as much as possible. After a few days, generally, everything comes back in order, and the child will have no sequel. In rare cases, the pain persists for several days, requiring additional tests: an ultrasound of the hips, x-rays (which may reveal a lesion), and possibly a blood test
Read More
Tic: the causes - Diseases
Diseases

Tic: the causes

The causes of tics are multi-factorial. That is, they are both neurobiological, psychological and environmental. For some specialists, tics would be equivalents of obsessive symptoms. This, because of their similarity to the compulsions of obsessive compulsive disorder. However, in many patients, there is no identifiable obsessive compulsive disorder
Read More
Thyroiditis: risk factors - Diseases
Diseases

Thyroiditis: risk factors

Thyroiditis occurs most often when there are certain risk factors, genetic, psychological or environmental. The risk factors for the development of autoimmune thyroiditis are: Sex : There is a clear female predisposition concerning thyroid pathologies (periodic screening for thyroid dysfunction is recommended for women over 50)
Read More
Appendicitis: treatments - Diseases
Diseases

Appendicitis: treatments

The only treatment is surgical appendectomy. Spontaneous evolution is the formation of an abscess that is likely to perforate in the abdominal cavity and the appendicitis crisis becomes more difficult peritonitis to treat. Surgery is necessary and is usually a simple procedure when appendicitis is taken on time
Read More