Hepatitis C: treatments

The treatments given to patients suffering from hepatitis C depend on various criteria that are determined by the medical specialist (genotype, more or less important involvement of the liver ...). Today, the best is to be cared for in a reference hospital hepatology service.

It is the liver biopsy, or non-invasive tests of fibrosis (blood test, ultrasound) that will determine the degree of damage to the liver (such as its degree of fibrosis). It is in considering all these elements that the treatment will be considered.

The treatments have evolved considerably in recent times, with the arrival of the new anti-viral direct action (ADD). Thus interferon (often responsible for significant adverse effects) is no longer recommended as the first treatment.

Until recently, treatment was based on the combination of two molecules: interferon, and ribavirin, with the addition of a third drug (telaprevir or boceprevir) for some forms of hepatitis C (genotype 1). It was a triple therapy, lasting six months to a year. The effectiveness of these treatments reached on average 80% of patients. But with often significant adverse effects (flu-like state, weight loss, anemia, fatigue, depression, dry skin ...).

The use of new treatments has made significant progress. In 2014, 14, 000 patients were cured. And 2015, an estimated 15, 000 new patients should be.

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