Medicinal Products


Generic drug of the therapeutic class: Dermatology
Active ingredients: Difluprednate
laboratory: Gerda

40 g tube
All forms


This dosage is more specifically intended for maintenance treatments after an attack treatment with another form of Epitopic more concentrated.
1. Preferred indications where local corticosteroid therapy is held for the best treatment:
- contact eczema,
- atopic dermatitis,
- lichenification.
2. Indications where local corticosteroid therapy is one of the usual treatments:
stasis dermatitis ("varicose eczema"),
- psoriasis,
- lichen,
- sclero-atrophic genital lichen,
- non-parasitic prurigo,
- dyshidrosis,
- granuloma annulare,
- discoid lupus erythematosus,
- Palmoplantar amicrobial pustulosis
- seborrheic dermatitis with the exception of the face,
- symptomatic treatment of pruritus of fungus mycosis.
3. Indications of circumstances for a short period of time:
insect bites and parasitic prurigo after etiological treatment.

Dosage EPITOPIC 0.02% Cream Tube 40 g

Applications are limited to 2 per day.
An increase in the number of daily applications could aggravate the adverse effects without improving the therapeutic effects.
The treatment of large areas requires monitoring of the number of tubes used.
For a rational use, it is advisable to apply the product in spaced keys, then to spread it with a plastic glove, until it is entirely absorbed.
Some dermatoses (psoriasis, atopic dermatitis ...) make it desirable to stop gradually.
It can be obtained by reducing the frequency of applications and / or by the use of a less strong or less dosed corticosteroid.

Against indications

- Hypersensitivity to any of the products contained in the preparation.
- Bacterial, viral, primitive and parasitic fungal infections even if they have an inflammatory component.
- Ulcerated lesions.
- Acne and rosacea.

Epitopic side effects

- Are to be feared in case of prolonged use but less frequently than with class I and II steroids (very strong and strong activity): cutaneous atrophy, telangiectasia (to be feared especially on the face), stretch marks (at the root of including members, and occurring more readily in adolescents), purpura ecchymotic secondary to atrophy, skin fragility.
- In the face, corticosteroids can create peri-oral dermatitis or create or aggravate rosacea (see contraindications, warnings and precautions for use).
- Can be observed delayed healing of sluggish wounds, pressure ulcers, leg ulcers (see contraindications).
- Possibility of systemic effects (see warnings: cushingoid syndrome, slowing of growth, acute adrenal insufficiency).
- have been reported: acneiform or pustular eruptions, hypertrichosis, depigmentation.

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