Medicinal Products

DOLTAQUE 200 mg

Generic drug of the therapeutic class: Analgesics
active ingredients: Ibuprofen
laboratory: EG Labo

Coated tablet
Box of 20
All forms

Indication

This medicine contains a nonsteroidal anti-inflammatory drug: ibuprofen. It is indicated, in the adult and the child of more than 40 kg (approximately 12 years), in the short treatment of fever and / or pain s such as headaches, flu-like states, dental pains, body aches and painful periods.

Dosage DOLTAQUE 200 mg Film-coated tablet Box of 20

Administration mode :
Oral way.
Swallow the tablet without chewing, with a large glass of water, preferably during the meal.
Dosage:
RESERVED FOR ADULTS AND CHILDREN OVER 40 KG (about 12 years old).
One tablet (200 mg), to be renewed if necessary after 6 hours.
In case of pain or fever more intense, 2 tablets 200 mg, to renew if necessary after 6 hours.
In all cases, do not exceed 6 tablets per day (1200 mg).
Frequency and timing of administration:
Systematic catches prevent fever or pain from oscillating.
They should be spaced at least 6 hours.

Against indications

CONTRAINDICATED:
- a history of allergy or asthma triggered by taking ibuprofen or substances of similar activity such as: other NSAIDs, aspirin,
- a history of allergy to the other constituents of the tablet,
- evolving gastroduodenal ulcer,
- severe hepatocellular insufficiency,
- severe renal insufficiency,
- severe uncontrolled heart failure,
- systemic lupus erythematosus,
- beyond 24 weeks of amenorrhea (5 months of pregnancy completed):
the administration during the 2nd and 3rd quarter exposes to:
. renal functional impairment in utero that can be observed as early as 12 weeks of amenorrhea (initiation of fetal diuresis): oligoamnios (most often reversible at the end of treatment), even anamnios especially during prolonged exposure ; at birth, renal insufficiency (reversible or not) may persist especially in case of late and prolonged exposure (with a risk of delayed severe hyperkalemia);
. a risk of cardiopulmonary involvement: partial or complete constriction in utero of the arterial canal. The constriction of the arterial duct may occur after 5 months and may lead to fetal or neonatal right heart failure or even fetal death in utero . This risk is even more important that the catch is close to the term (less reversibility). This effect exists even for a punctual catch;
. a risk of increased bleeding time for the mother and the child.
As a result, beyond 24 weeks of amenorrhea (5 months): any take even punctual is contraindicated. An inadvertent intake beyond 24 weeks of amenorrhea (5 months) justifies cardiac and renal, fetal and / or neonatal monitoring according to the exposure term. The duration of this monitoring will be adapted to the elimination half-life of the molecule.
Due to the presence of lactose, this drug is contraindicated in cases of congenital galactosemia, glucose-galactose malabsorption syndrome or lactase deficiency.
NOT RECOMMENDED :
- Chicken pox can exceptionally be the cause of serious infectious skin and soft tissue complications. To date, the role promoting NSAIDs in worsening these infections can not be ruled out. It is therefore prudent to avoid the use of this medicine in case of chicken pox.
- Breast-feeding: NSAIDs passing into breast milk, as a precaution, should be avoided in women who are breastfeeding.
- Associations advised against : other NSAIDs (including aspirin and other salicylates); oral anticoagulants; heparins in curative doses or in the elderly; lithium; methotrexate, used at doses greater than 15 mg / week.

Doltaque side effects

- Gastrointestinal effects:
Gastrointestinal disorders such as nausea, vomiting, gastralgia, dyspepsia, transit disorders, digestive ulcerations with or without haemorrhage, occult or non-occult haemorrhage have usually been reported. These are all the more frequent as the dosage used is high and the duration of treatment extended.
- Hypersensitivity reactions:
. Dermatological : rashes, rash, pruritus, edema, worsening of chronic urticaria,
. Respiratory : The onset of asthma attacks in some subjects may be related to an allergy to aspirin or a nonsteroidal anti-inflammatory drug (see contraindications).
. general : Quincke's edema.
- Effects on the central nervous system: ibuprofen may exceptionally be responsible for vertigo and headache.
- Other:
. exceptionally, severe infectious skin and soft tissue complications occurred during chickenpox;
. some rare cases of visual disturbances have been reported;
. oliguria, renal failure;
. the discovery of aseptic meningitis with ibuprofen should result in systemic lupus erythematosus or connective tissue disease.
- Some biological modifications could be observed:
. hepatic : transient increase of transaminases,
. haematological : agranulocytosis, haemolytic anemia.

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