Medicinal Products

DIALYSIS PERITO CONTINUOUS AMBUL19

Generic drug of the therapeutic class: Anesthesia, resuscitation, analgesics
Active Ingredients: Sodium Chloride, S-Sodium Lactate (E325), Calcium Chloride, Magnesium Chloride, Glucose
laboratory: Fresenius MC Deutsch Gmbh

Solution for peritoneal dialysis
Cardboard of 4 double pockets (staysafe) of 2000 ml
All forms

Indication

End stage chronic renal insufficiency (decompensated) irrespective of the origin and can be treated by peritoneal dialysis.

Dosage DIALYSE PERITO CONTINU AMBUL19 Solution for peritoneal dialysis Carton of 4 double pockets (staysafe) of 2000 ml

Dosage

Ambulatory Continuous Peritoneal Dialysis 19 is exclusively indicated for intraperitoneal use.

The type of treatment, the frequency of administration and the stasis time are defined by the attending physician.

Continuous Ambulatory Peritoneal Dialysis (CAPD)

Unless otherwise indicated, use 2000 ml of solution per exchange, 4 times daily (corresponding to a daily dose of 8000 ml). After a stasis time of 2 to 10 hours, the solution is drained.

The dosage should be adapted to each patient.

In case of pain due to abdominal distension at the beginning of treatment, the volume of treatment must be reduced.

In children, volumes of 500 ml and 1500 ml (30-40 ml / kg) are administered according to weight.

In patients of large size and / or who can tolerate larger volumes, and if residual renal function is lost, a larger dose will be required (2500 ml-3000 ml).

Automated Peritoneal Dialysis (APD)

If a machine (Sleepsafe cycler) is used for continuous or intermittent cyclic peritoneal dialysis, larger volume pouches (5000 ml) are used.

The cycler carries out the exchange of solutions according to the medical prescription recorded in the Sleepsafe machine.

Peritoneal dialysis is a long-term treatment with repeated administrations by the same method.

Mode and duration of administration

Patients must master the peritoneal dialysis technique before performing peritoneal dialysis at home.

They must be trained by qualified personnel.

Before performing dialysis at home, the attending physician will ensure that patients have sufficient knowledge of the technique.

In case of difficulty or doubt, the doctor should be contacted.

Repeat the infusions every day.

Treatment should be continued as long as renal replacement therapy is needed.

Continuous Ambulatory Peritoneal Dialysis (CAPD)

Warm the ready-to-use solution to body temperature. For bags smaller than 3000 ml, use a suitable heater. The warm-up time for a 2000 ml bag, with an initial temperature of 22 ° C, is about 120 minutes. Temperature control is performed automatically and is set at 39 ° C ± 1 ° C. For more information, refer to the heater's operating instructions.

The use of microwaves is not recommended because of the risk of overheating.

Introduce the appropriate volume through the catheter into the peritoneal cavity for a period of 5 to 20 minutes.

According to the doctor's instructions, the stasis lasts 2 to 10 hours (equilibrium time) then the solution is recovered in the drainage bag.

Depending on the desired osmotic pressure, Ambulatory Continuous Peritoneal Dialysis 19 may be used alternately with a higher or lower glucose peritoneal dialysis solution (higher or lower osmolarity).

Automated Peritoneal Dialysis (APD)

The Sleepsafe solution bag connectors are inserted into the available ports of the Sleepsafe machine and are automatically connected to the Set Sleepsafe by the machine. The machine checks the solution bag barcode and triggers an alarm if the bag does not match the prescription stored in the machine. After this check, the set tubing can be connected to the patient's catheter extension and treatment can begin. The Sleepsafe solution is automatically heated by the machine to body temperature during infusion. The duration of the stasis phases and the selection of the glucose concentrations are carried out according to the prescription stored in the machine (for more details, refer to the instructions for use of the sleep-safe cycler).

Against indications

From the solution itself:

Continuous Peritoneal Dialysis Ambulatory 19 should not be used in patients with lactic acidosis, severe hypokalemia and severe hypocalcemia, hypovolemia and hypotension.

Due to the presence of fructose, this drug is not suitable for patients with fructose intolerance (hereditary fructose intolerance).

Hereditary intolerance to unrecognized fructose should be ruled out before any administration in infants and children.

From the peritoneal dialysis technique:

Peritoneal dialysis treatment should not be used if:

· Recent abdominal surgery, recent abdominal injury, history of abdominal operations with fibrous adhesions, severe abdominal burn, abdominal perforation

· Extensive inflammatory skin conditions in the abdomen (dermatitis)

· Inflammatory bowel diseases (Crohn's disease, ulcerative colitis, diverticula)

· Localized peritonitis

· Internal or external abdominal fistula

· Umbilical hernias, inguinal hernias or other abdominal hernias

· Intra-abdominal tumors

Ileus

· Lung diseases (especially pneumonia)

· Sepsis

· Severe hyperlipidemia

· Rare cases of uremia not treatable by peritoneal dialysis

· Cachexia and significant weight loss, especially when adequate protein-based nutrition is impossible

· Where the patient is unable physically or mentally to follow peritoneal dialysis treatment as prescribed by the physician

Side effects Dialysis Perito Continuous Ambul19

Potential adverse effects may arise from the peritoneal dialysis process or may be induced by the solution itself.

Potential side effects caused by the solution itself:

· Aggravation or appearance of hyperparathyroidism,

· Electrolyte imbalances (in particular: hypokalemia, hypocalcemia),

· Imbalance of the water balance. Dehydration may result in rapid weight loss, hypotension and / or tachycardia. Hyperhydration can result in edema, hypertension and possibly dyspnea,

· Hyperglycemia,

· Hyperlipidemia or worsening of hyperlipidemia,

· Increase in body weight.

Potential side effects caused by the dialysis technique:

· Peritonitis, evidenced by turbid drainage solution. Subsequently, abdominal pain, fever and discomfort may occur or, in rare cases, a generalized infection of the blood (sepsis),

· Infection of the site of emergence of the catheter or tunnel, revealed by erythema, swelling, pain, oozing or crusts. If there is any sign of infection, consult the doctor immediately,

· Difficulties with infusion and drainage of the solution,

· Diarrhea and constipation,

· Breathing difficulties in inspiration,

· Hernias,

· Sensation of abdominal bloating, satiety (abdominal pain),

· Scapular pain.

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