Medicinal Products


Generic drug of the therapeutic class: Ophthalmology
Active ingredients: [LÃ © vobunolol, 1199]
laboratory: Allergan

Eye drops in solution
bottle of 5 ml
All forms


- Intraocular hypertonia.
- Chronic open angle glaucoma.

Dosage BETAGAN 05 PERCENT eye drops in solution 5 ml bottle

- Intraocular hypertonia.
- Chronic open angle glaucoma.

Against indications

· Hypersensitivity to the active substances or to any of the excipients.

The contraindications to general beta-blockers should be kept in mind, although the systemic effects of beta-blockers are observed only exceptionally after Eye instillations:

 · asthma or chronic obstructive pulmonary disease.

· Heart failure not controlled by treatment.

· Cardiogenic shock.

 · second and third degree non-paired atrioventricular blocks, Prinzmetal's angina.

· Sinus disease (including sino-atrial block).

· Bradycardia (<45 to 50 contractions per minute).

· Raynaud's disease and peripheral circulatory disorders.

· Untreated pheochromocytoma.

· Hypotension.

· Association with floctafenin (see section Interactions with other medicinal products and other forms of interaction ).

Betagan side effects


As with all beta-blocker eye drops, it can be observed:

 · a decrease in tear secretion (dry eye).

· Symptoms of eye irritation:

o Feeling of burning or tingling at the beginning of treatment.

o conjunctivitis, blachharitis, keratitis, corneal hypoesthesia.

· Visual disturbances including changes in the regimen (sometimes due to discontinuation of miotics), diplopia, ptosis.

 · Choroidal discard after glaucoma surgery (see Warnings and Precautions ).

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The undesirable effects of systemically administered beta-blockers should be kept in mind, although they are only exceptionally observed after ocular instillation.


The most frequently reported:

 · asthenia.

· Cooling of the ends.

 · bradycardia, Severe the case.

· Insomnia, nightmares and even depression.

· Digestive disorders (gastralgia, nausea, vomiting), diarrhea.

Much less often:

 · slowing of atrioventricular conduction or intensification of an existing atrioventricular block.

· Heart failure.

· Blood pressure drop.

· Bronchospasm.

· Hypoglycemia.

 · Raynaud's syndrome.

· Worsening of existing intermittent claudication.

· Skin manifestations including urticaria, angioedema (angioedema), skin rash, psoriasiform rash (see Warnings and Precautions section ).


In rare cases, it has been possible to observe the appearance of antinuclear antibodies that are only exceptionally associated with clinical manifestations such as lupus syndrome and that occur when treatment ceases.

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