Medicinal Products


Generic drug of the therapeutic class: Analgesics
active ingredients: Atropine sulfate
laboratory: Aguettant

Injectable solution
Box of 100 ampoules of 1 ml
All forms


- Pre-anesthesia: protection of vagal manifestations (bradycardia at induction).
- Atrioventricular or atrioventricular block.
- In myocardial infarction: prevention and treatment of atrioventricular blocks and sinus bradycardias.
- Symptomatic treatment of acute pain related to functional disorders of the digestive tract and bile ducts.
- Symptomatic treatment of spasmodic and painful urinary tract manifestations.
- Specific antidote in acute poisoning by anticholinesterase (organophosphorus insecticides and carbamates) or by parasympathomimetic or cholinomimetic drugs.

Dosage ATROPINE SULFATE AGUETTANT 1 mg / 1 ml Solution for injection Box of 100 ampoules of 1 ml

Parenteral administration (subcutaneous or intravenous slow depending on indication).
The specialty must be administered under medical supervision.
- Antispasmodic:
. in adults : 0.25 to 1 mg every 6 hours subcutaneously;
maximum dosage 2 mg per 24 hours.
. in children :
. between 2 and 6 years : 0.25 mg as a single dose subcutaneously.
. above 6 years : 0.50 mg as a single dose subcutaneously.
- Pre-anesthetic medication:
- in adults : 1 mg subcutaneously.
- in children :
. from 1 month to 30 months : 0.1 mg to 0.3 mg subcutaneously.
. from 30 months to 15 years : 0.1 mg to 0.5 mg subcutaneously.
- In cardiology:
in adults : 0.5 to 1 mg in slow IV.
- Intoxication (slow IV route):
2 mg immediately, then 1 mg every half hour until dry bronchial secretions.

Against indications

- Hyper-sensitivity to one of the compounds.
- Risk of glaucoma by closing the angle.
- Risk of urinary retention related to urethroprostatic disorders.
- Breast-feeding: The passage of atropine into breast milk may lead to overdose in the infant, with signs of neurological toxicity. In addition, atropine decreases the milk secretion. Therefore, if taking this medication is really necessary, breastfeeding is contraindicated.
Pregnancy 3rd quarter: Studies in animals have shown a teratogenic effect of atropine in a single species and at very high doses. In clinical practice, the use of atropine in a limited number of pregnancies has apparently not revealed any particular malformative or foetotoxic effect to date. However, further studies are needed to assess the consequences of exposure during pregnancy. Therefore, as a precaution, it is best not to use atropine during pregnancy.

Adverse effects Atropine Sulfate Aguettant

- Dry mouth.
- Thickening of bronchial secretions.
- Decrease of lacrimal secretion.
- Disorders of accommodation.
- Tachycardia, palpitation s.
- Constipation.
- Urinary retention.
- Excitability.
- Irritability, mental confusion in the elderly.
Dosage adjustment may reduce or eliminate these effects.

Popular Posts

Category Medicinal Products, Next Article