Medicinal Products

ATROPINE ALCON 1%

Generic drug of the therapeutic class: Ophthalmology
active ingredients: Atropine sulfate
laboratory: Alcon

eyewash
Bottle of 10 ml
All forms

Indication

· Treatment of uveal inflammations:

anterior uveitis (iritis, iridocyclitis) and posterior

o uveal reactions secondary to aggression or surgical treatment.

· Cycloplegia for refraction (essential for strabismus children) especially in the presence of accommodative strabismus.

· In some cases use to achieve an optical penalty in the treatment of amblyopia especially unilateral.

Dosage ATROPINE ALCON 1% Eye drops 10 ml bottle

Dosage

1 drop of eye drops contains 310 μg of active ingredient (atropine).

1 to 2 drops, 2 to 4 times a day.

The maximum dose for the child from 30 months to 15 years corresponds to the instillation of 3 times 2 drops of atropine at 0.30 percent per 24 hours.

Administration mode

As for all eye drops, carry out, in order, the following operations:

· Wash hands thoroughly.

· Avoid touching the eye or eyelids with the tip of the vial.

· To instil this eye drop, look upward and gently pull the lower eyelid down.

· With the eye closed, cleanly wipe the excess, especially on the cheek.

· To avoid ingestion especially in children see section Warnings and precautions for use .

· In order to avoid systemic effects induced by the passage of atropine into the general circulation through the lacrimal ducts and by oral ingestion, it is recommended, especially in children and the elderly, to compress the internal angle of the eye for 1 minute after each instillation and wipe the excess on the cheek.

· Close the bottle after use.

· If concomitant treatment with another eye drops, allow 15 minutes for instillation.

Against indications

· In case of hypersensitivity to atropine or to any of the excipients of eye drops (especially to mercurial derivatives).

· In patients at risk for angle closure glaucoma.

· In case of breastfeeding.

Side effects Atropine Alcon

Ocular adverse effects

· Risk of acute glaucoma by closing the angle (see section 4.3 ).

· Annoying mydriasis, prolonged accommodation disturbances.

· Local irritation, tingling, possible allergic reaction.

Vehicle-related

Due to the presence of phenylmercuric nitrate: risk of contact eczema, depigmentation.

Systemic side effects

Atropine eye drops enter the systemic circulation and may cause systemic effects especially in children and the elderly (see sections Dosage and method of administration "method of administration" and Warnings and precautions for use ) .

The undesirable effects are mainly neurological and psychiatric:

· In particular: agitation, hyperexcitability or sudden drowsiness, confusion,

· More rarely at therapeutic doses: convulsions and hallucinations,

· The child and the elderly have variable responses to atropine eye drops.

Other signs of atropine impregnation are common:

· Redness of the face, tachycardia, dry mouth.

· Fever in children, rarely severe except in case of overdose.

· Digestive disorders :

o constipation especially in the elderly,

o in the premature newborn: Abdominal distention, ileus, occlusion.

Great caution in administration is essential in this population of premature newborns.

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