Medicinal Products

ATROPINE (SULFATE) AGUETTANT 0.5 mg / mL

Generic drug of the therapeutic class: Anesthesia, resuscitation, analgesics
active ingredients: Atropine sulfate
laboratory: Aguettant

Injectable solution
Box of 10 ampoule of 1 mL bottles
All forms

Indication

- Pre-anesthesia: protection of vagal manifestations (bradycardia at induction).
- Atrioventricular or atrioventricular block.
- In myocardial infarction: prevention and treatment of atrioventricular blocks and sinus bradycardias.
- Symptomatic treatment of acute pain related to functional disorders of the digestive tract and bile ducts.
- Symptomatic treatment of spasmodic and painful urinary tract manifestations.
- Specific antidote in acute poisoning by anticholinesterase (organophosphorus insecticides and carbamates) or by parasympathicomimetic or cholinomimetic drugs.

Dosage ATROPINE (SULFATE) AGUETTANT 0.5 mg / mL Solution for injection Box of 10 Ampoules 1 mL bottles

Subcutaneous or slow intravenous route, as indicated.
The specialty must be administered under medical supervision.
Antispasmodic (SC route):
. in adults : 0.25 to 1 mg every 6 hours, maximum dose: 2 mg / 24 h.
. in children :
above 6 years : 0.50 mg as a single dose,
between 2 and 6 years : 0.25 mg single dose.
- Pre-anesthetic medication (SC route):
. in adults : 1 mg.
. in children (from 30 months to 15 years) : 0.1 mg to 0.5 mg.
. in infants (1 to 30 months) : 0.1 mg to 0.3 mg.
- In cardiology (slow IV route): 0.5 to 1 mg.
- In case of intoxication (slow IV route): 2 mg immediately, then 1 mg every 1/2 hour until dry bronchial secretions.

Against indications

CONTRAINDICATED:
This medicine should not be given if:
- Hyper-sensitivity to one of the compounds,
- risk of glaucoma by closing the angle,
- risk of urinary retention related to urethroprostatic disorders.
- in case of breastfeeding: the passage of atropine into breast milk may lead to overdose in the infant, including signs of neurological toxicity. In addition, atropine decreases the milk secretion. Therefore, if taking this medication is really necessary, breastfeeding is contraindicated.
NOT RECOMMENDED :
This drug is generally not recommended during the last trimester of pregnancy: studies in animals have shown a teratogenic effect of atropine in a single species and at very high doses. In clinical practice, the use of atropine in a limited number of pregnancies has apparently not revealed any particular malformative or foetotoxic effect to date. However, further studies are needed to assess the consequences of exposure during pregnancy. Therefore, as a precaution, it is best not to use atropine during pregnancy.

Adverse effects Atropine Aguettant

- dry mouth,
- thickening of bronchial secretions,
- decrease of lacrimal secretion,
- disturbances of accommodation,
- tachycardia, palpitations,
- constipation,
- urine retention,
- excitability,
- irritability, mental confusion in the elderly.
Dosage adjustment may reduce or eliminate these effects.

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