Generic drug of the therapeutic class: Analgesics
active ingredients: Acetylsalicylic acid, Ascorbic acid (E300)
laboratory: Bristol Myers Squibb
Sparkling effervescent tablet
Box of 2 tubes of 15
This medicine contains aspirin and vitamin C.
It is indicated in adults and children from 30 kg (approximately 9-15 years) in the symptomatic treatment of mild to moderate pain and / or febrile states.
Dosage ASPIRINE VITAMIN C OBERLIN 500mg / 200mg Effervescent tablet scored Box of 2 Tubes of 15
Drink immediately after complete dissolution of the effervescent tablet in a large glass of water.
Pains of mild to moderate intensity and / or febrile states:
Reserved for adults and children from 30 kg (about 9 to 15 years).
§ In children, it is imperative to respect the dosages defined according to the weight of the child and to choose a suitable presentation. Approximate ages by weight are given for information.
The recommended daily dose of acetylsalicylic acid is approximately 60 mg / kg / day, divided into 4 or 6 doses, approximately 15 mg / kg every 6 hours or 10 mg / kg every 4 hours.
o For children weighing 30 to 40 kg (approximately 9 to 13 years), the dosage is 1 effervescent tablet per dose, to be renewed if necessary after 6 hours, without exceeding 4 tablets per day.
o For children weighing 41 to 50 kg (approximately 12 to 15 years), the dosage is 1 effervescent tablet per dose, to be renewed if necessary after 4 hours, not exceeding 6 tablets per day .
§ For adults and children weighing more than 50 kg (from about 15 years old):
The maximum recommended daily dosage is 3 g of aspirin, 6 tablets per day.
The usual dosage is 1 effervescent tablet 500 mg, to be renewed if necessary after 4 hours minimum. In case of pain or fever more intense, 2 tablets 500 mg, to renew if necessary after 4 hours minimum, without exceeding 6 effervescent tablets per day .
§ For elderly subjects:
The maximum recommended daily dosage is 2 g of aspirin, or 4 effervescent tablets per day.
The usual dosage is 1 effervescent tablet 500 mg, to be renewed if necessary after 4 hours minimum. In case of pain or fever more intense, 2 tablets 500 mg, to renew if necessary after 4 hours minimum, without exceeding 4 effervescent tablets per day .
Frequency of administration:
Systematic catches prevent pain or fever oscillations.
The intakes should be regularly spaced, including at night, preferably 6 hours, and at least 4 hours: comply with the dosage specified above.
Duration of the treatment:
The patient should be informed not to use acetylsalicylic acid more than 3 days in case of fever and 5 days in case of pain without the advice of a doctor or dentist.
This medicine is CONTRAINDICATED in the following situations:
Hypersensitivity to acetylsalicylic acid or to any of the excipients,
· History of asthma caused by salicylates or substances of similar activity, including nonsteroidal anti-inflammatory drugs,
· Pregnancy beyond 24 weeks of amenorrhea (5 months) for doses greater than 100 mg per day (see section on Pregnancy and lactation ),
· Evolving gastroduodenal ulcer,
· Any constitutional or acquired haemorrhagic disease,
· Haemorrhagic risk,
· Severe liver failure,
· Severe renal insufficiency,
· Severe uncontrolled heart failure,
· In combination with methotrexate at doses greater than 20 mg / week (see section 4.5 ), and for anti-inflammatory doses (≥ 1 g per dose and / or ≥ 3) g per day), or for analgesic or antipyretic doses (≥ 500 mg per dose and / or <3 g per day) of acetylsalicylic acid,
In combination with oral anticoagulants for anti-inflammatory doses (≥ 1 g per dose and / or ≥ 3 g daily), or for analgesic or antipyretic doses (≥ 500 mg per dose and / or <3 g per day) ) of acetylsalicylic acid and in a patient with a history of peptic ulcer disease (see section 4.5 ).
Side effects Aspirin Vitamin C Oberlin
· Gastrointestinal effects:
o abdominal pain,
o obvious digestive haemorrhages (hematemesis, melena ...) or occult, responsible for iron deficiency anemia. These haemorrhages are all the more frequent as the dosage is higher,
o gastric ulcers and perforations.
· Effects on the central nervous system:
o headache, vertigo,
o feeling of decreased hearing,
o tinnitus that is usually the hallmark of an overdose.
· Hematological effects:
o haemorrhagic syndromes (epistaxis, gingivorragia, purpura, ...) with increased bleeding time. This action persists for 4 to 8 days after stopping acetylsalicylic acid. It can create a hemorrhagic risk, in case of surgical intervention.
· Hypersensitivity reaction:
o urticaria, skin reactions, anaphylactic reactions, asthma, Quincke's edema.
· Reye's syndrome in children (see Warnings and precautions for use ).
· Linked to ascorbic acid
At doses higher than 1g / day in vitamin C, possibility of:
o digestive disorders (gastric burns, diarrhea),
o urinary disorders (oxalic, cystic and / or risk lithiases).