Medicinal Products

ARTEX 5 mg

Generic drug of the therapeutic class: Cardiology and angiology
Active ingredients: Tertatolol
laboratory: Servier

Breakable coated tablet
Box of 30
All forms



Dosage ARTEX 5 mg scored tablet 30 pack

One tablet a day in a morning intake.
Tertatolol, tablet, can be taken before, during, or after breakfast, food intake does not alter the bioavailability.
In case of severe arterial hypertension, a higher dosage may be prescribed.
Tertatolol can be combined with other antihypertensive therapies.
- In patients with hepatic insufficiency (prothrombin level below 70%), the dosage will be reduced to half a tablet per day.
- Renal insufficiency, as long as the creatinine clearance is greater than or equal to 10 ml / min, as well as the age of the patient do not impose particular adaptation doses.

Against indications

This medicine MUST NEVER be used in the following cases:
- hypersensitivity to tertatolol,
- asthma and obstructive chronic bronchopneumopathies,
- heart failure not controlled by treatment,
- cardiogenic shock,
- non-paired second and third degree atrioventricular blocks,
- angina of Prinzmetal,
- sinus disease (including sinoatrial block),
- bradycardia (<45 to 50 contractions per minute),
- Raynaud's phenomenon and peripheral arterial disorders,
- untreated pheochromocytoma,
- hypotension,
- history of anaphylactic reaction,
- very severe renal insufficiency (creatinine clearance less than 10 ml / min) as a precaution in the absence of currently available studies,
- combination with floctafenine, sultopride (see interactions).
- This medication is NOT RECOMMENDED for combination with amiodarone.
- Breast-feeding: Beta-blockers are excreted in the milk. The risk of developing hypoglycaemia and bradycardia has not been evaluated; therefore, and as a precaution, breastfeeding is not recommended during the course of treatment.

Artex side effects

- The most frequently reported:
. asthenia,
. cooling of the ends,
. bradycardia, severe if any,
. digestive disorders (gastralgia, nausea, vomiting),
. incapacity,
. insomnia, nightmares.
- Much more rarely:
. slowing of atrioventricular conduction or intensification of an existing atrioventricular block,
. heart failure,
. blood pressure drop,
. bronchospasm,
. hypoglycemia,
. Raynaud's syndrome,
. worsening of existing intermittent claudication,
. various skin manifestations including psoriasiform eruptions (see warnings and precautions for use).
In rare cases, it has been possible to observe the appearance of antinuclear antibodies which only exceptionally accompany clinical manifestations such as lupus syndrome and cede at the end of treatment.

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