Medicinal Products


Generic Drug Therapeutic Class: Neurology-Psychiatry
active ingredients: St. John's Wort
laboratory: Arkopharma

Pill box of 42
All forms


Traditionally used in mild and transient depressive manifestations.

Dosage ARKOCAPS MILLEPERTUIS 185 mg Capsule Pill Box 42

Oral way. Reserved for adults.
2 to 3 capsules a day to leave during the day, to take with a big glass of water.
The intake should preferably be performed at the same times.

Against indications

In combination with ciclosporin, irinotecan, oral anticoagulants, antiretroviral protease inhibitors and non-nucleoside reverse transcriptase inhibitors, anticonvulsants (except gabapentin and vigabatrin) (carbamazepine, ethosuximide, felbamate, fosphenytoin, lamotrigine, phenobarbital, phenytoin, primidone, tiagabine, topiramate, valproic acid, valpromide) (see section interactions).
- Pregnancy: There are no reliable data on teratogenesis in animals. Clinically, no particular malformative or fetotoxic effect has emerged to date. However, the monitoring of exposed pregnancies is insufficient to exclude any risk. Therefore, as a precaution, it is best not to use this medicine during pregnancy.
- This medicinal product is not recommended when taking medication containing digoxin, theophylline, an oral contraceptive, an anti-epileptic drug, an antidepressant or an anti-migraine drug of the triptan family (see section on interactions).

Side effects Arkogelules St. John's wort

- A few cases of serotonin syndrome have been reported in the literature in elderly patients treated concomitantly with a serotonin reuptake inhibitor antidepressant and St. John's wort.
- Digestive disorders and skin reactions like photosensitization have been reported.

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