Generic drug of the therapeutic class: Allergology
active ingredients: Paracetamol, Promethazine
Box of 10
Symptomatic treatment of nasal hypersecretion in acute nasopharyngeal conditions with headache and / or fever.
NB: In view of the general clinical signs of bacterial infection, a systemic antibiotic therapy should be considered.
Dosage ALGOTROPYL 200 mg / 5 mg suppository Box of 10
RESERVED FOR CHILDREN WEIGHING BETWEEN 13 AND 16 KG (ABOUT 2 TO 5 YEARS).
In children, it is imperative to respect the dosages defined according to the weight of the child and therefore to choose a suitable presentation. Approximate ages by weight are given for information.
The recommended daily dose of paracetamol depends on the weight of the child: it is about 60 mg / kg / day, to be divided into 4 doses, or about 15 mg / kg every 6 hours.
Due to the risk of local toxicity; the administration of a suppository is not recommended beyond 4 times a day, and the rectal treatment should be as short as possible.
In case of diarrhea, suppository administration is not recommended.
The dosage is 1 suppository 200 mg paracetamol to be renewed if necessary after 6 hours without exceeding 4 suppositories per day.
Evening intakes should be preferred because of the pronounced sedative effect of promethazine, especially at the beginning of treatment.
In case of severe renal insufficiency (creatinine clearance less than 10 ml / min), the interval between two doses will be at least 8 hours.
This medicine is CONTRAINDICATED in the following cases:
· Due to the presence of paracetamol:
o hypersensitivity to paracetamol,
o hepatocellular insufficiency;
· Due to the presence of promethazine:
o hypersensitivity to promethazine,
o antecedents of agranulocytosis,
o risk of urinary retention related to urethral disorders,
o risk of glaucoma by closing the angle,
· Recent history of proctitis, anitis or rectorrhagia.
Algotropyl side effects
Related to the presence of paracetamol:
· A few rare cases of allergic accidents are manifested by simple skin rashes with erythema or urticaria and require discontinuation of treatment;
· Very exceptional cases of thrombocytopenia have been reported.
Linked to the suppository form:
Possible rectal or anal irritation.
Linked to the presence of promethazine:
The pharmacological characteristics of the molecule cause undesirable effects of unequal intensity and are dose-related or non-dose-related (see section 5.1 Pharmacodynamic properties).
· Neurovegetative effects:
o sedation or drowsiness, more marked at the beginning of treatment;
o anticholinergic effects such as dryness of the mucous membranes, constipation, accommodation disorders, mydriasis, heart palpitations, risk of urinary retention;
o orthostatic hypotension;
o disturbances of balance, vertigo, loss of memory or concentration;
motor incoordination, tremors;
o mental confusion, hallucinations;
o more rarely and especially in infants, effects with excitation type: agitation, nervousness, insomnia;
· Awareness Reactions:
o erythema, eczema, pruritus, purpura, possibly giant urticaria,
o edema, more rarely angioedema,
o anaphylactic shock,
· Hematological disorders:
o leukopenia, neutropenia, exceptional agranulocytosis;
o Hemolytic anemia.