Medicinal Products

AETOXISCEROL BUFFER 0.5% (10 mg / 2 mL)

Generic drug of the therapeutic class: Cardiology and angiology
active ingredients: Lauromacrogol 400
laboratory: Kreussler Pharma

IV injectable solution
Box of 5 ampoules of 2 ml
All forms

Indication

Sclerosis of varicose veins and varicose veins of the foot and the perimalleolar region.

Dosage AETOXISCEROL BUFFER 0.5% (10 mg / 2 mL) Solution for injection IV Box of 5 ampoules of 2 ml

Intravenous (IV) injectable route.

It is desirable to start each injection session by administering a minimal test dose.

1 to 4 ml of injectable solution per session (1/2 to 2 ampoules).

Make sure of the position of the needle in the varix.

Against indications

· Allergy known to lauromarogol 400 or any of its excipients

· Patients immobilized for prolonged periods

· Recent thrombo-embolic episode

· Evolutionary cancer

· Foramen ovale known symptomatic ovale

· Erysipelas and lymphangitis in the area to be treated

Side effects Aetoxiscerol Buffer 0.5%

Adverse effects, observed with different frequencies, are listed below by organic class.

Immune system disorders: anaphylactic shock, angioedema, urticaria, asthma

Nervous system disorders: headache, migraine, paresthesia, unconsciousness, confusional state, vertigo

Ocular disorders: phosphenes, scotomes, amaurosis

Heart disorders: palpitations. Due to the arrhythmogenic properties of lauromacrogol, possibility of cardiovascular collapse due to the systemic passage of the product.

Vascular disorders:

· Neovascularization, hematoma

· Superficial thrombophlebitis, phlebitis

· deep vein thrombosis

· pulmonary embolism,

· Vasovagal syncope,

· Vasculitis, leukocytoclastic vasculitis

Respiratory, thoracic and mediastinal disorders: dyspnoea, feeling of oppression

Gastrointestinal disorders: dysgeusia, nausea

Skin and subcutaneous tissue disorders:

Hyperpigmentation of the skin, bruise

Allergic dermatitis, contact urticaria, erythema

Hypertrichosis (in the treated area)

General disorders and accidents related to the site of administration:

Injection site pain (short term), injection site thrombosis (local intravarious blood clots)

Induration, edema

Local necrosis-like reactions, particularly in the skin and underlying tissues (and in some rare cases, in the nerves), have been observed in the treatment of varicose veins of the legs after inadvertent injection into the skin. surrounding tissues (para-venous injection). The risk is increased with increasing concentrations and volumes injected.

Fever, hot flash

Investigations: abnormal blood pressure

Lesions and intoxications: lesion of a nerve

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